# The Effect of Statin Therapy on Hemorheological Parameters of Patients with Clinically Silent Ischemic Foci of the Brain

## TL;DR

This study examines how statin therapy affects blood flow properties in patients with silent brain ischemia.

## Contribution

The study shows that statins modify hemorheological parameters in patients with silent cerebral ischemia.

## Key findings

- Statin therapy was found to influence whole blood and plasma viscosity.
- Erythrocyte aggregability and deformability were modified by statin use.
- The Quemada model was used to analyze changes in erythrocyte behavior.

## Abstract

Hemorheology is a branch of science that studies and explains the causes of blood flow disorders. In many vascular disorders whole blood viscosity, plasma viscosity, aggregability, and deformability of erythrocytes can be a diagnostic factor. In this paper we analyze whether statin therapy affects hemorheological values in a group of patients with clinically diagnosed silent ischemic foci of the brain (CSVCL). The study includes an analysis of the hemorheological parameter values such as whole blood viscosity, plasma viscosity, and selected biochemical parameters. Aggregability and deformability of erythrocytes were determined using the mathematical Quemada model. Our results indicate a modifying effect of statins on hemorheological parameters.