# The iron woman: a case report of contemporary cardiac support

## TL;DR

This case report describes a female patient with severe heart failure who received multiple advanced cardiac treatments before undergoing a heart transplant.

## Contribution

The novelty lies in the comprehensive documentation of sequential device-based therapies applied in a single patient with advanced heart failure.

## Key findings

- The patient received a full range of device-based therapies for heart failure and mitral regurgitation.
- The case highlights the progression from temporary to durable mechanical support and eventual heart transplantation.
- The report reviews indications and anatomical considerations for various cardiac devices.

## Abstract

Modern cardiovascular practice utilizes various devices and procedures to treat functional and structural heart disease.

We report an interesting case of a female patient with heart failure with reduced ejection fraction (HFrEF) and severe mitral regurgitation who received the full spectrum of available device-based therapies including mitral transcatheter edge-to-edge repair, percutaneous mitral annuloplasty with the Carillon device, temporary mechanical circulatory support, durable left ventricular assist device, and eventually cardiac transplantation.

Management of HFrEF and functional mitral regurgitation is a common clinical issue for which numerous devices may be utilized to improve patient symptoms and outcomes. In this report, we review indications, supporting data, and anatomical relationships of some of these devices. We also highlight stepwise progression to advanced heart failure requiring temporary and durable mechanical circulatory support followed ultimately by heart transplantation.