# Metastatic Malignant Phaeochromocytoma in Ascitic Fluid: Cytological Diagnosis of a Rare Entity

**Authors:** Scarlet Fiona Brockmoeller, Sigfred Lajara, Samer Khader

PMC · DOI: 10.1111/cyt.70003 · Cytopathology · 2025-06-30

## TL;DR

This paper presents a rare case of metastatic phaeochromocytoma found in peritoneal fluid, highlighting the importance of clinical history and cell block preparation for accurate diagnosis.

## Contribution

The first documented case of metastatic phaeochromocytoma in peritoneal fluid in cytopathology literature.

## Key findings

- Metastatic phaeochromocytoma was identified in peritoneal fluid through cytopathological evaluation.
- The case underscores the role of clinical history and cell block preparation in diagnosing rare metastatic tumors.

## Abstract

In summary, a review of the literature showed that there are only isolated case reports of ruptured pheochromocytoma and to the best of our knowledge this report is the first to document metastatic phaeochromocytoma in peritoneal fluid within the cytopathology literature. Our case report emphasises the importance of clinical history in the context of the cytopathologic evaluation, and good cell block preparation, which allows the use of IHCs in challenging cases as it may lead to the discovery of unusual metastatic sources.

## Linked entities

- **Diseases:** pheochromocytoma (MONDO:0004974)

## Full-text entities

- **Diseases:** Malignant Phaeochromocytoma (MESH:D009369), pheochromocytoma (MESH:D010673)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12345389/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12345389/full.md

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Source: https://tomesphere.com/paper/PMC12345389