# Adult Measles Outbreak in New Jersey: The Dangers of Declining Vaccination Rates

**Authors:** Allyson E Whitsett, Yaser Salah, Kevin J Callagy, Aubin Attila, Sameh Girgis

PMC · DOI: 10.7759/cureus.87885 · 2025-07-14

## TL;DR

A measles outbreak in New Jersey highlights the risks of low vaccination rates and the importance of immunization in preventing disease spread.

## Contribution

This case study emphasizes the public health risks of declining vaccination rates through a rare adult measles case.

## Key findings

- An unvaccinated adult male's measles case led to secondary transmission to four unvaccinated individuals.
- Public health authorities had to implement outbreak containment measures after delays in isolation protocols.
- The case underscores the importance of vaccination in maintaining herd immunity and preventing outbreaks.

## Abstract

This case highlights a rare presentation of measles in an unvaccinated adult male in New Jersey, emphasizing the risks posed by declining vaccination rates. The outbreak linked to this case illustrates the public health dangers of vaccine hesitancy and insufficient immunization coverage.

A 32-year-old male presented with five days of worsening fever, nausea, vomiting, diarrhea, and a spreading maculopapular rash. Physical examination revealed petechial lesions on the soft palate, a lacy-patterned rash, and tachycardia. Laboratory findings included thrombocytopenia, electrolyte imbalances, hyperglycemia, and elevated liver enzymes.

Serologic testing confirmed a diagnosis of measles. The patient received supportive care, but delays in isolation protocols resulted in secondary transmission to four unvaccinated contacts, including three children and one adult. Public health authorities were alerted, and outbreak containment measures were implemented.

This case underscores the critical role of vaccination in preventing measles outbreaks and the need for proactive public health strategies to address vaccine hesitancy. It serves as a reminder of the consequences of declining vaccination rates and the importance of maintaining herd immunity to protect vulnerable populations.

## Linked entities

- **Diseases:** measles (MONDO:0004619)

## Full-text entities

- **Genes:** GPT (glutamic--pyruvic transaminase) [NCBI Gene 2875] {aka AAT1, ALT, ALT1, GPT1, SGPT}, SLC17A5 (solute carrier family 17 member 5) [NCBI Gene 26503] {aka AST, ISSD, NSD, SD, SIALIN, SIASD}
- **Diseases:** tick-borne illnesses (MESH:D017282), rubella (MESH:D012409), pneumonia (MESH:D011014), hypokalemia (MESH:D007008), coryza (MESH:D003139), tachycardia (MESH:D013610), hyperglycemia (MESH:D006943), pressure (MESH:D003668), autism (MESH:D001321), cough (MESH:D003371), weakness (MESH:D018908), viral exanthems (MESH:D014777), infected (MESH:D007239), lymphadenopathy (MESH:D008206), encephalitis (MESH:D004660), Measles (MESH:D008457), conjunctivitis (MESH:D003231), thrombocytopenia (MESH:D013921), MMR (MESH:D009107), vomiting (MESH:D014839), death (MESH:D003643), infectious disease (MESH:D003141), gastrointestinal symptoms (MESH:D012817), diarrhea (MESH:D003967), febrile (MESH:D000071072), maculopapular rash (MESH:D005076), syphilis (MESH:D013587), nausea (MESH:D009325), fever (MESH:D005334), lesions (MESH:D009059)
- **Chemicals:** ondansetron (MESH:D017294), MMR (-), Vitamin A (MESH:D014801), acetaminophen (MESH:D000082)
- **Species:** Homo sapiens (human, species) [taxon 9606], Measles morbillivirus (no rank) [taxon 11234]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12345067/full.md

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Source: https://tomesphere.com/paper/PMC12345067