The evolution of personalized stroke thrombectomy
Emmanuel O. Mensah, Yew-Weng Fong, Sandeep Muram, Christopher S. Ogilvy, Philipp Taussky

TL;DR
This paper reviews how personalized stroke thrombectomy can be adapted to a wider range of patients, using new imaging and techniques to improve outcomes.
Contribution
The paper introduces strategies for personalizing stroke thrombectomy based on lesion characteristics, patient factors, and procedural innovations.
Findings
Personalized thrombectomy considers factors like infarct size, low NIHSS scores, and unique biomarkers.
Procedural innovations include tailored device use and alternative access strategies for complex cases.
Future improvements involve advanced imaging, biomarkers, and optimized devices for underrepresented populations.
Abstract
Stroke is a leading cause of disability and death worldwide, with acute ischemic stroke accounting for most cases. Mechanical thrombectomy is a widely accepted treatment modality in appropriately selected patients, demonstrating improved functional outcomes through safe and effective recanalization. However, traditional trials have focused on a narrow subset of patients, limiting its applicability to diverse populations who would otherwise benefit from thrombectomy. Advances in neurovascular imaging, device innovation, and procedural techniques are driving a paradigm shift toward personalized stroke thrombectomy. This review explores personalization strategies across various domains, including lesion-specific considerations such as medium vessel occlusions (MeVOs), basilar artery occlusions (BAOs), and tandem lesions, as well as patient-specific factors like infarct size, low NIHSS…
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Taxonomy
TopicsAcute Ischemic Stroke Management · Cerebrovascular and Carotid Artery Diseases · Stroke Rehabilitation and Recovery
