Clinical and imaging diagnosis of pediatric testicular microlithiasis: a physician’s dilemma

TL;DR

This paper reviews the challenges in diagnosing testicular microlithiasis in children and suggests a management approach to avoid delayed cancer detection.

Contribution

The paper proposes a standardized diagnostic algorithm for pediatric testicular microlithiasis based on current evidence and clinical practices.

Findings

Testicular microlithiasis in children lacks definitive diagnostic and management guidelines.

Continued follow-up and routine scrotal examination are recommended to prevent delayed diagnosis of potential tumors.

Ultrasonographic surveillance is advised for high-risk cases despite not being mandatory.

Abstract

Testicular microlithiasis (TM) is a relatively rare and incompletely understood condition, particularly in the pediatric population. Its clinical significance and optimal diagnostic and therapeutic management remain subjects of ongoing debate. In order to clarify current practices and guide clinical decision-making, we conducted a literature review of recent studies published using the search terms testicular microlithiasis, testicular calculi, testicular neoplasm, and children. The primary objective of this review was to propose a standardized diagnostic management algorithm based on the available evidence. The nature of testicular microlithiasis remains a subject of ongoing debate. In the absence of definitive evidence, continued follow-up appears to be the safest approach to minimize the risk of delayed diagnosis in the event of malignant transformation or tumor development. Routine scrotal examination should be encouraged and properly taught, particularly to adolescents and their caregivers. Ultrasonographic (US) surveillance, while not mandatory, should be considered when accessible, especially in individuals with additional risk factors.

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