# A Rare Case Report of Contrast Media-induced Sympathetic Crashing Acute Pulmonary Edema

## TL;DR

This case report describes a rare instance of a severe lung condition triggered by contrast dye during a CT scan and highlights the importance of early treatment.

## Contribution

The paper presents a rare clinical case of contrast-induced SCAPE and emphasizes early recognition and treatment strategies.

## Key findings

- A 70-year-old man developed SCAPE after contrast-enhanced CT and required high-dose nitroglycerin and ventilation.
- Early recognition and treatment with NIPPV and vasodilators led to full recovery.
- Contrast-induced SCAPE is rare but life-threatening and requires prompt intervention.

## Abstract

Sympathetic crashing acute pulmonary edema (SCAPE), also known as flash pulmonary edema or hypertensive acute heart failure, is a critical condition characterized by a rapid escalation of sympathetic outflow, excessive afterload, and worsening heart failure. Although rare, contrast media-induced pulmonary edema is a severe adverse reaction, occurring in 0.001–0.008% of patients receiving intravenous contrast and accounting for 10–20% of lethal contrast reactions.

A 70-year-old male developed acute respiratory distress shortly after undergoing an outpatient, contrast-enhanced computed tomography. Despite treatment for suspected anaphylaxis, the patient’s condition continued to deteriorate until a diagnosis of SCAPE was ultimately recognized. Treatment with high-dose nitroglycerin, non-invasive positive pressure ventilation (NIPPV), and eventual intubation resulted in the patient’s full recovery.

This report highlights the importance of recognizing SCAPE in patients presenting with sudden dyspnea after contrast administration and emphasizes the need for early intervention with NIPPV and vasodilators to reduce morbidity and mortality.