# Characteristics and Outcomes of Patients with Self-directed Violence Presenting to Trauma Centers in the United States

**Authors:** Gregory Jasani, Garrett Cavaliere, Rana Bachir, Sarah Van Remmen, Mazen El Sayed

PMC · DOI: 10.5811/westjem.42022 · Western Journal of Emergency Medicine · 2025-07-18

## TL;DR

This study analyzes patients with self-inflicted injuries in US trauma centers, finding high injury severity and mortality rates.

## Contribution

The study identifies factors associated with survival in patients with self-directed violence at US trauma centers.

## Key findings

- Most patients had mental/personality disorders, alcohol or substance use disorders.
- Penetrating trauma was the most common injury mechanism, with cutting/piercing being more frequent than firearms.
- The mortality rate at hospital discharge was 21.7% among these patients.

## Abstract

Psychiatric conditions are common presentations to the emergency department, and their prevalence has been steadily increasing. Part of this spectrum of presentations is self-directed violence. Self-directed violence involves suicidal acts and non-suicidal self-injuries that can result in serious morbidity and mortality. This study examines characteristics and outcomes of patients who presented to US trauma centers with self-inflicted injuries and identifies factors associated with survival to hospital discharge in this patient population.

We extracted data in a retrospective, observational manner from the 2020 National Trauma Data Bank (NTDB) 2020. The NTDB includes data from over 900 trauma centers (900/2,294 total trauma centers in the United States, 39.2%). We performed a descriptive analysis of characteristics, injury patterns and outcomes. All variables were tabulated by outcome (died: yes/no). We then conducted a multivariable logistic regression using a stepwise technique to identify factors associated with the patients’ survival to hospital discharge.

A total of 12,824 patients with self-inflicted injuries were included in this analysis. Their median age was 35 years (interquartile range 25–50), and they were mostly males (74.7%) and White (69.6%). Patients were mostly transported by ground ambulance (78.9%) to Level I (60.6%) and Level II (33.5%) trauma centers. Most patients had a pre-existing condition (70.2%). These included mental/personality disorder (48.2%), alcohol use disorder (11.5%), and substance use disorder (17.7%). The most common mechanism of injury was penetrating trauma (71.6%), followed by blunt trauma (18.0%) and burns (1%). Cutting/piercing was the most common penetrating mechanism (60%) compared with firearm-related trauma (40%). Severe injury (Injury Severity Score ≥ 16) was present in 32.8% of patients. A positive alcohol screen and/or a positive drug screen were reported in 30.2% and 31.2% of patients, respectively. Most patients were admitted to hospital (86%). Overall mortality rate at hospital discharge was 21.7%. We identified Important factors associated with survival to hospital discharge in this patient population.

Patients with self-inflicted injuries treated at US trauma centers have high rates of injury severity and a high mortality rate. This study sheds light on the complex and resource-intensive care needed for this vulnerable patient population.

## Full-text entities

- **Diseases:** penetrating trauma (MESH:D020197), mental/personality disorder (MESH:D010554), Psychiatric conditions (MESH:D001523), Injury (MESH:D014947), substance use disorder (MESH:D019966), alcohol use disorder (MESH:D000437), burns (MESH:D002056)
- **Chemicals:** alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

37 references — full list in the complete paper: https://tomesphere.com/paper/PMC12342402/full.md

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Source: https://tomesphere.com/paper/PMC12342402