# LEGO® as a versatile platform for building reconfigurable low-cost lab equipment

**Authors:** Diane N. Jung, Kailey E. Shara, Carson J. Bruns, Yuliang Zhang, Yuliang Zhang

PMC · DOI: 10.1371/journal.pone.0326938 · PLOS One · 2025-08-12

## TL;DR

LEGO® can be used to build low-cost, reconfigurable lab equipment that is sustainable and effective for scientific research.

## Contribution

The paper demonstrates LEGO®-based lab tools as a cost-effective and sustainable alternative to conventional equipment.

## Key findings

- LEGO®-based tools like syringe pumps, orbital shakers, and microcentrifuges can be built for under $174 USD.
- LEGO® tools produced calcium carbonate microparticles comparable to commercial equipment.
- Customizable LEGO® shakers enabled a wider range of particle characteristics than commercial models.

## Abstract

Laboratory equipment is critical for automating tasks in modern scientific research, but often limited by high costs, large footprints, and sustainability concerns. Emerging strategies to provide low-cost research automation tools include microfluidic devices, open-hardware devices, 3D printing, and LEGO® products. LEGO®-based equipment may be advantageous with respect to sustainability, since their inherent modularity enables disassembly, re-purposing and re-use. To explore the feasibility and cost savings of replacing conventional lab equipment with LEGO®-based alternatives, we developed and characterized the performance of three LEGO® TechnicTM laboratory tools: a syringe pump, an orbital shaker, and a microcentrifuge. These three machines share 384 pieces in common and can be constructed in series (687 pieces, <$83 USD) or in parallel (1215 pieces, <$174 USD). As a proof of concept, calcium carbonate microparticles were synthesized and isolated using the LEGO®-based and analogous commercial equipment, yielding comparatively similar results. Moreover, the ability to program custom shake profiles for the LEGO®-based orbital shaker gave access to a wider range of particle characteristics than the commercial shaker. We propose that the high cost savings and reusability of LEGO®-based lab tools extends beyond their well-established efficacy in K-12 STEM education to an attractive resource for budget-, space- and/or sustainability-conscious laboratories.

## Linked entities

- **Chemicals:** calcium carbonate (PubChem CID 10112)

## Full-text entities

- **Chemicals:** calcium carbonate (MESH:D002119)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12342335/full.md

## References

74 references — full list in the complete paper: https://tomesphere.com/paper/PMC12342335/full.md

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Source: https://tomesphere.com/paper/PMC12342335