# BioModels’ Model of the Year 2023

**Authors:** Rahuman S. Malik Sheriff, Hiroki Asari, Henning Hermjakob, Wolfgang Huber, Thomas Quail, Silvia D. M. Santos, Amber M. Smith, Virginie Uhlmann

PMC · DOI: 10.3389/fsysb.2024.1363884 · Frontiers in Systems Biology · 2024-02-27

## TL;DR

This paper highlights the 2023 BioModels competition, which promotes mathematical modeling in biology and recognizes early-career researchers for their impactful models.

## Contribution

The paper introduces the Model of the Year 2023 competition to encourage reproducibility and FAIR model sharing by early-career researchers.

## Key findings

- The competition emphasizes reproducibility and FAIR principles in model sharing.
- Winning models offer insights into cell division, protein stability, and cell fate.
- The initiative supports early-career researchers in the life sciences.

## Abstract

Mathematical modeling is a pivotal tool for deciphering the complexities of biological systems and their control mechanisms, providing substantial benefits for industrial applications and answering relevant biological questions. BioModels’ Model of the Year 2023 competition was established to recognize and highlight exciting modeling-based research in the life sciences, particularly by non-independent early-career researchers. It further aims to endorse reproducibility and FAIR principles of model sharing among these researchers. We here delineate the competition’s criteria for participation and selection, introduce the award recipients, and provide an overview of their contributions. Their models provide crucial insights into cell division regulation, protein stability, and cell fate determination, illustrating the role of mathematical modeling in advancing biological research.

## Full-text entities

- **Genes:** STAT5A (signal transducer and activator of transcription 5A) [NCBI Gene 6776] {aka MGF, STAT5}, JAK2 (Janus kinase 2) [NCBI Gene 3717] {aka JTK10}
- **Diseases:** blood disorders (MESH:D006402)
- **Chemicals:** PIs (MESH:D010716)
- **Species:** Homo sapiens (human, species) [taxon 9606], Xenopus laevis (African clawed frog, species) [taxon 8355]

## Full text

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12342021/full.md

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Source: https://tomesphere.com/paper/PMC12342021