# Additional Cover

**Authors:** Silas A. Buck, Samuel J. Mabry, Tenzin Kunkhyen, Zilu Yang, Sophie A. Rubin, Jinting Yang, Claire E. J. Cheetham, Zachary Freyberg

PMC · DOI: 10.1111/acel.70199 · Aging Cell · 2025-08-12

## TL;DR

The paper explores how dVGLUT affects dopamine neuron mitochondria in aging and Parkinson's disease, with differences between sexes.

## Contribution

The study identifies dVGLUT as a mediator of sex differences in mitochondrial function in dopamine neurons.

## Key findings

- dVGLUT mediates sex differences in dopamine neuron mitochondrial function during aging.
- Sex differences in mitochondrial function are also observed in a Parkinson's disease model.

## Abstract

Cover legend: The cover image is based on the article dVGLUT Is a Mediator of Sex Differences in Dopamine Neuron Mitochondrial Function Across Aging and in a Parkinson's Disease Model by Silas A. Buck et al., https://doi.org/10.1111/acel.70096.

## Linked entities

- **Proteins:** VGlut (Vesicular glutamate transporter)
- **Diseases:** Parkinson's disease (MONDO:0005180)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12341790/full.md

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Source: https://tomesphere.com/paper/PMC12341790