# Safety and efficacy of aneurysms treated with endovascular devices (The SEATED Study)

## TL;DR

This study aims to collect nationwide data on aneurysm treatments using endovascular devices to assess their safety and effectiveness in real-world settings.

## Contribution

The study introduces a nationwide consortium to pool data on less commonly used endovascular devices, enabling pragmatic real-world analysis.

## Key findings

- Centres using the same device showed variation in antiplatelet and follow-up protocols.
- The study highlights the feasibility of a nationwide consortium to analyze data on recent endovascular devices.
- Initial recruitment is expected to include around 5000 patients for comprehensive analysis.

## Abstract

To create a nationwide consortium to gather all the data related to advanced devices used for aneurysm treatment and conduct pragmatic real-world studies despite the variations among all centres. The strength of this study will be in pooling data of the less commonly used recent devices where there is less evidence. The study will be prospective and retrospective where the initial recruitment figure is expected to be around 5000 patients.

To assess how endovascular techniques vary among different UK centres, we illustrate the results of initial surveys that were sent to those centres across the United Kingdom using a single device, the pipeline embolization device with vantage technology (PEDV).

Although the centres were using the same device, the antiplatelet protocol varied from one centre to another as well as follow-up protocols according to the local experience, patient clinical status or even according to the adjuncts uses (e.g., adjunct coiling).

The illustrated results show that although the centres were using the same device, the antiplatelet protocol varied from one centre to another. Also, follow-up protocols vary from one centre to another according to the local experience, patient clinical status or even according to the adjuncts used (e.g., adjunct coiling). This exemplar serves to illustrate that a nationwide consortium can pool and analyse data of any recent endovascular device.

Obtaining nationwide data regarding safety, efficacy as well as risk factors for aneurysm recurrence when using recent devices. This study will add valuable data regarding the less commonly used recent devices where there is less evidence.