# Laryngeal Tuberculosis Mimicking Laryngeal Carcinoma: A Case Report

**Authors:** Zineb Yammouri, Smail Chaouche, Ghita Alami, Fadoua Harmouch, Badreddine Alami, Y. Lamrani, Nawal Hammas, Meryem Boubbou, Mustapha Maaroufi

PMC · DOI: 10.7759/cureus.87828 · Cureus · 2025-07-13

## TL;DR

A case of laryngeal tuberculosis mistaken for cancer shows the importance of accurate diagnosis to avoid unnecessary surgery.

## Contribution

This case report highlights the diagnostic challenge of distinguishing laryngeal tuberculosis from laryngeal carcinoma.

## Key findings

- Laryngeal tuberculosis can clinically and radiologically mimic laryngeal carcinoma.
- A biopsy confirmed tuberculosis in a patient initially suspected of having cancer.

## Abstract

Laryngeal tuberculosis (LTB) is a rare form of extrapulmonary tuberculosis that can clinically and radiologically resemble laryngeal carcinoma, leading to potential misdiagnosis. We report the case of a 53-year-old man with a history of chronic smoking, no known tuberculosis or BCG vaccination, who presented with progressive dyspnea, dysphonia, and significant weight loss. Laryngoscopy revealed ulcerative lesions involving the anterior commissure, right ventricular strip, arytenoid fold, and epiglottis. CT imaging suggested malignancy, but a biopsy confirmed LTB with pulmonary involvement. The patient responded favorably to anti-tuberculous therapy, with near-complete resolution after two months. This case highlights the diagnostic challenge of differentiating LTB from malignancy. Awareness of this rare presentation is essential, especially in tuberculosis (TB)-endemic regions, to avoid unnecessary surgical intervention and ensure prompt medical treatment.

## Linked entities

- **Diseases:** laryngeal tuberculosis (MONDO:0005819), tuberculosis (MONDO:0018076), laryngeal carcinoma (MONDO:0002358)

## Full-text entities

- **Diseases:** dyspnea (MESH:D004417), TB (MESH:D014376), tuberculous (MESH:D014390), ulcerative lesions (MESH:D014456), dysphonia (MESH:D055154), pulmonary involvement (MESH:C566343), extrapulmonary tuberculosis (MESH:D000092225), Laryngeal Carcinoma (MESH:D007822), malignancy (MESH:D009369), weight loss (MESH:D015431), LTB (MESH:D014387)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12341445/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12341445/full.md

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Source: https://tomesphere.com/paper/PMC12341445