# Dosimetric analysis of orthogonal collimator configuration in volumetric modulated arc therapy planning: a comparative study

**Authors:** Xin Huang, Chenlei Guo, Shuangtong Liu, Kuo Men, Hui Wang

PMC · DOI: 10.3389/fonc.2025.1612643 · Frontiers in Oncology · 2025-07-29

## TL;DR

This study compares radiation therapy plans using different collimator angles, finding that orthogonal angles improve dose distribution and reduce damage to nearby healthy tissues.

## Contribution

The study introduces orthogonal collimator angles in dual-arc VMAT to improve dosimetric outcomes without compromising plan quality.

## Key findings

- Orthogonal collimator angles improved dose conformity and reduced doses to organs at risk.
- Gamma pass rates remained above 95%, indicating good delivery accuracy.
- Monitor units decreased in breast and laryngeal plans but increased in rectal plans.

## Abstract

In volumetric modulated arc therapy (VMAT), collimator angle selection impacts dose distribution and plan quality. Conventional VMAT plans use dual arcs with collimators set at 0˚. This study explores the dosimetric effects of using orthogonal collimator angles (0˚ and 90˚) in dual-arc VMAT.

Sixty patients with head and neck, thoracic, and abdominal tumors were analyzed. Two VMAT plans were generated: Plan A (0˚ collimator angle) and Plan B (0˚ and 90˚ collimator angles). Dosimetric endpoints included conformity index (CI), gradient measure (GM), homogeneity index (HI), dose to organs at risk (OARs), mean dose to normal tissues (Dmean, NT), monitor units (MU), and gamma pass rate (GPR).

Plan B improved dosimetric outcomes over Plan A. HI decreased by 0.03 in the rectum, 0.01 in the breast, and 0.01 in the larynx. GM decreased by 0.15 cm in the rectum, 0.05 cm in the breast, and 0.01 cm in the larynx. OAR doses were reduced across sites, with notable decreases in the bladder (−4.62 Gy), left anterior descending artery (−3.99 Gy), and spinal cord (−1.79 Gy). Dmean,NT was slightly reduced in the rectum, breast and larynx. MU increased in rectum plans (+41 MU), but decreased in the breast and laryngeal plans by 38 MU and approximately 73 MU, respectively. All plans achieved GPR > 95%.

Incorporating orthogonal collimator angles (0˚ and 90˚) in dual-arc VMAT enhances dose conformity and spares OARs without compromising target coverage or delivery accuracy. This approach is clinically applicable with minimal workflow changes.

## Full-text entities

- **Diseases:** head and neck, thoracic, and abdominal tumors (MESH:D006258)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12340999/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12340999/full.md

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Source: https://tomesphere.com/paper/PMC12340999