# Testing Whether Established Risk Factors for Future Eating Disorder Onset Predict Future Overweight/Obesity Onset: A Prospective Study

**Authors:** Eric Stice, Yuko Yamamiya

PMC · DOI: 10.21203/rs.3.rs-7230160/v1 · Research Square · 2025-08-06

## TL;DR

This study explores whether risk factors for eating disorders also predict future overweight or obesity in young women.

## Contribution

The study identifies specific psychological factors that uniquely predict future overweight/obesity onset.

## Key findings

- Body dissatisfaction, negative affect, and feeling fat increased the risk of future overweight/obesity.
- Lower-than-expected body weight reduced the risk of future overweight/obesity.
- High body dissatisfaction had the strongest predictive effect, with elevated negative affect amplifying risk.

## Abstract

The evidence that overweight and obesity often cooccur with eating disorders, overeating and binge eating increase risk for future eating disorder onset, and a prevention program that reduces overeating prevents future eating disorder onset suggests factors that increase risk for eating disorders may also increase risk for unhealthy weight gain. We test whether predictors of future eating disorder onset, which include both risk factors and prodromal symptoms, also predict future onset of overweight or obesity.

Data were collected from 1 952 adolescent girls and young women who completed annual assessments over a 3-year period. Among them, our final sample consisted of 1 669 participants (Mean age = 19.4, SD = 4.9) who met the inclusion criteria. Logistic regression models tested whether each established eating disorder risk factor predicted future onset of overweight or obesity. Classification tree analysis tested for interactions among the predictors.

Body dissatisfaction (OR = 1.43, 95% CI [1.23, 1.66], p < .001), negative affect (OR = 1.20, 95% CI [1.05, 1.37], p = .006), and feeling fat (OR = 1.37, 95% CI [1.19, 1.58], p < .001) increased risk for future onset of overweight/obesity and lower-than-expected body weight reduced risk (OR = 0.62, 95% CI [0.37, 0.83], p = .014), though only body dissatisfaction (OR = 1.25, 95% CI [1.04, 1.51], p = .017) and lower-than-expected body weight (OR = 0.65, 95% CI [0.38, 0.87], p = .026) showed unique predictive effects in a multivariate model. The classification tree model indicated that high body dissatisfaction showed the strongest predictive effect, and that elevated negative affect further amplified risk; results also revealed a distinct risk pathway characterized by low psychosocial impairment.

Results identified several risk and protective factors for overweight/obesity onset, which may work together in a synergistic faction to increase risk for overweight/obesity.

## Linked entities

- **Diseases:** obesity (MONDO:0011122), eating disorder (MONDO:0005451)

## Full-text entities

- **Diseases:** Obesity (MESH:D009765), Eating Disorder (MESH:D001068), binge eating (MESH:D002032), unhealthy weight gain (MESH:D015430), Overweight (MESH:D050177)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

46 references — full list in the complete paper: https://tomesphere.com/paper/PMC12340894/full.md

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Source: https://tomesphere.com/paper/PMC12340894