# Quantitative imaging of 478-keV prompt gamma rays from Boron neutron capture reactions

## TL;DR

This paper presents a new gamma-ray imaging detector for measuring boron concentrations in cancer treatment, improving the accuracy of BNCT.

## Contribution

A specialized gamma-ray imaging detector was developed and validated for precise BNCT measurements.

## Key findings

- A linear correlation was established between gamma-ray production and boron concentration using phantom samples.
- The detector effectively monitored boron dose distribution during neutron irradiation in a treatment facility.

## Abstract

The accurate imaging and quantitative measurement of 478-keV prompt gamma rays are critical for advancing boron neutron capture therapy (BNCT), a promising cancer treatment. Although numerical simulations have indicated that such measurements are feasible, their practical application has proven challenging. This study introduces a gamma-ray imaging detector designed specifically for precise BNCT measurements. Using boron-rich phantom samples, we successfully imaged 478-keV gamma rays and established a linear correlation between gamma-ray production and boron concentration. Furthermore, applying this technique in a recognized BNCT treatment facility demonstrated the detector’s effectiveness in monitoring boron dose distribution during neutron irradiation, both in pre-treatment diagnostics and throughout the treatment process.