# Case Report: Crohn’s disease with coexisting mesenteric schwannoma

**Authors:** Juntao Lu, Yuqi Qiao, Tianrong Wang, Zhijun Cao

PMC · DOI: 10.3389/fmed.2025.1621976 · Frontiers in Medicine · 2025-07-29

## TL;DR

A 22-year-old man with Crohn’s disease also had a rare mesenteric schwannoma, which complicated diagnosis and treatment.

## Contribution

This case report adds to the limited literature on Crohn’s disease coexisting with a mesenteric schwannoma.

## Key findings

- Crohn’s disease and a mesenteric schwannoma were diagnosed in a single patient.
- Diagnostic imaging suggested Crohn’s disease but failed to accurately identify the schwannoma preoperatively.
- Surgical resection confirmed the schwannoma diagnosis.

## Abstract

This case report discusses a rare instance of Crohn’s disease coexisting with a mesenteric schwannoma in a 22-year-old man. The patient initially presented with painful defecation and recurrent fever. Diagnostic procedures, including MRI, CTE, and FDG-PET/CT, revealed signs consistent with Crohn’s disease and an enlarged abdominal “lymph node” suspected to be a schwannoma. Despite exclusive enteral nutrition, the nodule persisted, complicating further treatment. Surgical resection confirmed the diagnosis of schwannoma. This report highlights the diagnostic challenges and treatment complexities when Crohn’s disease coexists with rare tumors such as schwannomas.

## Linked entities

- **Diseases:** Crohn’s disease (MONDO:0005011), schwannoma (MONDO:0002546)

## Full-text entities

- **Diseases:** Crohn's disease (MESH:D003424), tumors (MESH:D009369), fever (MESH:D005334), schwannoma (MESH:D009442), painful (MESH:D010146)
- **Chemicals:** FDG (MESH:D019788)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12339563/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12339563/full.md

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Source: https://tomesphere.com/paper/PMC12339563