# A Unique Case of Gallstone Ileus in a Patient With Crohn's Disease: Stone Impaction in an Ileal Adenocarcinoma

**Authors:** Tommaso Antenucci, Rosario Arena

PMC · DOI: 10.1002/ccr3.70793 · Clinical Case Reports · 2025-08-11

## TL;DR

A rare case of gallstone ileus in a Crohn's disease patient is linked to an ileal adenocarcinoma.

## Contribution

Highlights the importance of considering malignancy in Crohn's patients with new intestinal strictures.

## Key findings

- Gallstone ileus occurred secondary to an ileal adenocarcinoma in a Crohn's disease patient.
- Crohn's disease increases the risk of both gallstones and gastrointestinal malignancies.
- New strictures in Crohn's patients should prompt evaluation for underlying malignancy.

## Abstract

Gallstone ileus represents an uncommon etiology of mechanical intestinal obstruction. Individuals with Crohn's disease are predisposed to both increased gallstone formation and a heightened risk of gastrointestinal malignancy. This case highlights the necessity of excluding malignancy when evaluating newly developed strictures in this patient population.

## Linked entities

- **Diseases:** Crohn's disease (MONDO:0005011)

## Full-text entities

- **Diseases:** gallstone (MESH:D042882), strictures (MESH:D003251), Gallstone Ileus (MESH:D045823), intestinal obstruction (MESH:D007415), malignancy (MESH:D009369), Crohn's Disease (MESH:D003424), gastrointestinal malignancy (MESH:D005770), Ileal Adenocarcinoma (MESH:D007078)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12339411/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12339411/full.md

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Source: https://tomesphere.com/paper/PMC12339411