# A case report of allergic eczematoid dermatitis around hemodialysis access due to iodine-containing disinfectant

**Authors:** Xiaomei Lu, Jing He, Liansheng Ren, Rong Yang, Shuhuan Liu, Jingying Bai, Yueqiu Tang, Yi Zeng, Yunmin Wang, Wei Zhang, Dan Zhu

PMC · DOI: 10.3389/fimmu.2025.1627179 · Frontiers in Immunology · 2025-07-28

## TL;DR

A patient developed a skin rash near their dialysis access site due to an allergy to iodine-containing disinfectants.

## Contribution

This case report highlights iodine-containing disinfectants as a potential allergen in hemodialysis patients.

## Key findings

- The patient's dermatitis improved after switching to alcohol disinfection and using oral steroids.
- Allergic reactions at dialysis access sites can be avoided by identifying and avoiding allergens like iodine.
- Switching from an AVF to a TCC dialysis access triggered a similar allergic response in the patient.

## Abstract

We report here a case of allergic eczematoid dermatitis related to hemodialysis access. The patient was initially suspected to have puncture needle allergies or dialyzer reactions until the patient develops a similar response after switching from an arteriovenous fistula (AVF) to a tunneled cuffed catheter (TCC) for dialysis. Thereby, we highly suspected that the allergen was the iodine-containing disinfectant used prior to dialysis, and the patient was ultimately diagnosed with iodine-containing disinfectant allergy. The patient’s dermatitis improved remarkably after switching to alcohol disinfection as well as taking oral steroids. Early identification and diagnosis of allergic reactions at the vascular access site can avoid contacting with allergens, accordingly prevent complications like infection and loss of precious vascular accesses in these patients.

## Linked entities

- **Chemicals:** iodine (PubChem CID 807), alcohol (PubChem CID 702)

## Full-text entities

- **Diseases:** dermatitis (MESH:D003872), allergic (MESH:D004342), infection (MESH:D007239)
- **Chemicals:** iodine (MESH:D007455), alcohol (MESH:D000438), steroids (MESH:D013256)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12337784/full.md

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Source: https://tomesphere.com/paper/PMC12337784