# Hematopoietic stem cell transplantation 50 years: from pioneering to leading, the Chinese protocol has reshaped the global landscape

## TL;DR

Chinese advancements in hematopoietic stem cell transplantation have transformed global practices, starting from the first successful transplant in Asia to developing the widely adopted 'Beijing Protocol'.

## Contribution

The development and global adoption of the 'Beijing Protocol' for haploidentical stem cell transplantation.

## Key findings

- China's first hematopoietic stem cell transplant in 1964 marked the beginning of its leadership in the field.
- The 'Beijing Protocol' established in 2016 is now the mainstream approach for haploidentical transplants worldwide.
- Chinese innovations have significantly influenced and reshaped global stem cell transplantation practices.

## Abstract

造血干细胞移植作为治愈大多数血液系统疾病的有效手段，于中国的发展历程堪称辉煌。1964年，陆道培成功完成亚洲首例、全球第四例造血干细胞移植术，开启中国在该领域的征程。2000年，黄晓军完成世界首例非体外去T细胞单倍型相合造血干细胞移植术，并持续优化，使其体系在2016年被世界骨髓移植协会命名为“北京方案”，如今成为全球单倍型移植的主流方案。新型细胞治疗的出现革新了传统造血干细胞移植模式。中国学者从学习西方起步，一路奋进，重塑了全球造血干细胞移植格局。