# Chinese expert consensus on the diagnosis, treatment, and prevention of carbapenem-resistant Enterobacteriaceae（CRE）infection in patients with hematological malignancies（2025）

## TL;DR

This paper presents a Chinese expert consensus on diagnosing, treating, and preventing CRE infections in blood cancer patients.

## Contribution

A new expert consensus guideline for managing CRE infections in hematological malignancy patients in China.

## Key findings

- CRE infections pose a high risk and mortality in hematological malignancy patients.
- Experts discussed CRE epidemiology, diagnostics, treatment, and infection control strategies.
- The consensus aims to standardize CRE management in Chinese healthcare settings.

## Abstract

细菌耐药已成为全球公共卫生领域的重大挑战，碳青霉烯类耐药肠杆菌科细菌（CRE）出现并在全球范围内快速播散，对人类健康构成极大威胁。血液肿瘤患者是CRE感染的高危人群，且感染的病死率亦较高。在血液肿瘤患者中，如何诊治和防控CRE感染已成为当前细菌感染领域最为棘手的问题。为规范我国血液肿瘤患者CRE感染诊治方案和防控策略，国内血液、感染等领域专家对CRE感染的流行病学特点、实验室检测、治疗原则、主要治疗药物和方案、CRE感染及定植的危险因素、医院感染防控等方面进行讨论，形成了本共识。