# Chinese diagnosis and treatment guideline for pediatric acute promyelocytic leukemia（2025）

## TL;DR

This paper presents a new Chinese guideline for diagnosing and treating pediatric acute promyelocytic leukemia based on evidence-based medicine.

## Contribution

The novel contribution is the development of a comprehensive, evidence-based guideline specifically for pediatric APL in China.

## Key findings

- APL has a 5-year disease-free survival rate exceeding 90%.
- Current diagnostic and treatment strategies for pediatric APL still face significant challenges.
- The guideline aims to improve overall pediatric APL management in China.

## Abstract

急性早幼粒细胞白血病（APL）是急性髓系白血病的一种特殊亚型，常以严重出血为首发表现，起病凶险。虽然APL的5年无病生存率已达90％以上，但在儿童APL诊断和治疗策略上仍存在诸多问题。为了推动儿童APL诊疗水平的全面提升，我们制定了基于循证医学证据的中国儿童APL诊疗指南。