# Outcome of CC7 transfer to median nerve and deep branch of ulnar nerve for patients with global brachial plexus avulsion

**Authors:** Yuzhou Liu, Hu Yu, Jingbo Liu, Jie Lao

PMC · DOI: 10.3389/fmed.2025.1604280 · Frontiers in Medicine · 2025-07-28

## TL;DR

This study compares two nerve transfer techniques for brachial plexus avulsion, finding one method improves intrinsic muscle recovery.

## Contribution

A modified CC7 transfer technique combining median nerve and deep ulnar nerve shows improved intrinsic muscle recovery in brachial plexus avulsion patients.

## Key findings

- Modified CC7 transfer achieved M3, M2, and M1 recovery in abductor digiti minimi, unlike conventional transfers.
- Motor unit potentials appeared in abductor digiti minimi and dorsal interosseous muscle in the modified group.
- Modified technique did not negatively impact median nerve recovery.

## Abstract

As for global brachial plexus avulsion, the recoveries of intrinsic muscles are not satisfying after nerve transfers.

A retrospective review of 31 patients treated with different CC7 transfers after GBPA was carried out. The modified group: CC7 transfer to median nerve and DBUN by medial antebrachial cutaneous nerve (MACN). The conventional group: CC7 transfer to median nerve. The mean follow-up period was 3 years.

After CC7 transfers, one patient got M3, one patient got M2 and two patients got M1 in abductor digiti minimi (ADM) in the modified group, while no patients had recovery in ADM in the conventional group. The recoveries of abductor pollicis brevis (APB) were similar between two groups. Motor unit potentials (MUP) of ADM and dorsal interosseous muscle (DIM) appeared in 4 and 2 patients respectively after surgery in the modified group. Nobody gained MUP of ADM or DIM in the conventional group. There were no statistical differences of MUP in APB, compound motor action potential (CMAP) in FDPI and FCR between two groups.

CC7 transfer to median nerve and DBUN by pedicled ulnar nerve and MACN could initially make intrinsic muscles regeneration in patients with GBPA, while not affect the recovery of median nerve.

## Full-text entities

- **Diseases:** brachial plexus avulsion (MESH:D020516)
- **Chemicals:** CC7 (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12336263/full.md

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Source: https://tomesphere.com/paper/PMC12336263