# Nonsurgical Extradural Hematoma in Intensive Care: Predictive Factors for Progression

**Authors:** Lamiae Bennis, Youssef Elouardi, Imane Oussayeh, Mohammed Khallouki

PMC · DOI: 10.7759/cureus.87742 · Cureus · 2025-07-11

## TL;DR

This study identifies factors that predict whether a brain bleed called extradural hematoma will worsen in ICU patients not undergoing surgery.

## Contribution

The study identifies specific clinical and radiological factors predictive of EDH progression in nonsurgically managed patients.

## Key findings

- Temporal location of hematoma is associated with progression (p = 0.046).
- Large hematoma volume significantly predicts progression (p = 0.002).
- Early CT scanning is strongly linked to EDH progression (p = 0.0005).

## Abstract

Introduction

Extradural hematoma (EDH) is a potentially life-threatening neurosurgical emergency that typically requires urgent surgical evacuation to prevent neurological deterioration and death. However, a subset of patients can be managed nonsurgically in the ICU with close neurological monitoring. This study aimed to identify predictive factors for EDH progression in patients managed conservatively in the ICU.

Materials and methods

We conducted a retrospective analytical study of patients admitted to the surgical ICU of Mohammed VI University Hospital Center in Marrakesh over a five-year period. The study included patients with post-traumatic EDH who were initially managed nonsurgically.

Results

A total of 61 cases were included, of which 12 patients eventually required delayed surgery. EDH progression was significantly associated with temporal location (p = 0.046), large hematoma volume (p = 0.002), coagulopathy (p = 0.04), a Glasgow Coma Scale score ≥13 at admission (p = 0.04), and early CT scanning (p = 0.0005).

Conclusions

Our findings suggest that the presence of certain predictive factors may indicate a higher risk of EDH progression. These cases require close monitoring and preparedness for surgical intervention to optimize patient outcomes.

## Full-text entities

- **Diseases:** death (MESH:D003643), hematoma (MESH:D006406), EDH (MESH:D006407), neurological deterioration (MESH:D009422), coagulopathy (MESH:D001778)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12335870/full.md

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Source: https://tomesphere.com/paper/PMC12335870