# Cotard’s Syndrome in a Patient With Paranoid Schizophrenia: A Case Report of a Type I Presentation

**Authors:** Mariam Tsuladze, Khatia Sulaberidze

PMC · DOI: 10.7759/cureus.87731 · Cureus · 2025-07-11

## TL;DR

A rare case of Cotard's syndrome in a non-depressed person with paranoid schizophrenia was successfully treated with medication.

## Contribution

Highlights a non-typical presentation of Cotard's syndrome in a schizophrenia patient without depression.

## Key findings

- The patient exhibited nihilistic delusions without depressive symptoms.
- Treatment with haloperidol, diazepam, and levomepromazine was effective.
- Early identification of Cotard's syndrome can improve outcomes in schizophrenia patients.

## Abstract

This report presents a rare case of Cotard's syndrome in a middle-aged woman with paranoid schizophrenia. The patient developed symptoms characterized by Cotard's syndrome in the psychiatric ward after several days of treatment. Our patient's presentation was not typical: she had a nihilistic delusion but lacked depressive symptoms. The patient was successfully treated with haloperidol, diazepam, and levomepromazine.

This case demonstrates the importance of identifying Cotard’s condition in non-depressed, schizophrenic individuals, as prompt management can improve outcomes.

## Linked entities

- **Chemicals:** haloperidol (PubChem CID 3559), diazepam (PubChem CID 3016), levomepromazine (PubChem CID 3916)
- **Diseases:** paranoid schizophrenia (MONDO:0001484)

## Full-text entities

- **Diseases:** Cotard's Syndrome (MESH:D005359), depressed (MESH:D003866), schizophrenic (MESH:D012559), Paranoid Schizophrenia (MESH:D012563), psychiatric (MESH:D001523), Cotard's condition (MESH:D002908), delusion (MESH:D063726)
- **Chemicals:** levomepromazine (MESH:D008728), haloperidol (MESH:D006220), diazepam (MESH:D003975)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12335855/full.md

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Source: https://tomesphere.com/paper/PMC12335855