# Evaluation of the analgesic efficacy of ultrasound-guided quadratus lumborum block for laparoscopic renal surgery: a randomized controlled trial

**Authors:** Lei Shen, Xiangjun Liu, Yuxiang Meng, Chenyang Shi, Zhibiao Xu, Yu Wang, Kang Zhou, Su Liu, Linlin Zhao

PMC · DOI: 10.1186/s12871-025-03268-8 · BMC Anesthesiology · 2025-08-09

## TL;DR

This study shows that a specific ultrasound-guided block reduces pain and improves recovery after kidney surgery.

## Contribution

Demonstrates the effectiveness of quadratus lumborum blocks in laparoscopic renal surgery for pain management and recovery.

## Key findings

- QLB group had lower pain scores at rest and during movement up to 24 hours post-surgery.
- QLB reduced opioid use and adverse reactions like nausea and vomiting.
- QLB improved recovery rates and time to first walk and exhaust.

## Abstract

To evaluate the analgesic efficacy of ultrasound-guided quadratus lumborum block (QLB) for laparoscopic renal surgery.

Sixty-eight patients who underwent unilateral laparoscopic renal surgery were enrolled. All patients were separated into two groups: group QLB (n = 34) and group C (n = 34). Patients in the QLB group underwent unilateral anterior QLB before the induction of anesthesia. Patients in group C underwent laparoscopic renal surgery with no block. Postoperative NRS scores at rest and during movement at 6, 12, 24, 48 h were assessed. Remedial analgesia and the incidence of adverse reactions within 48 h after surgery were recorded. The quality of recovery was compared at 24 and 48 h after the operation via the postoperative quality recovery scale.

At 6, 12, 24 h postoperatively, the QLB group had lower resting and moving NRS scores than did the C group (P < 0.05). The QLB group had lower numbers of PCAs, remedial analgesia and incidences of nausea and vomiting within 48 h (P < 0.05). The time to first walk and exhaust was shorter in the QLB group (P < 0.05). The recovery rates of nociceptive and emotional factors at 24, 48 h in the QLB group were greater (P < 0.05). The recovery rates of the activities of daily living (ADL) factors at 24 h in the QLB group were greater (P < 0.05).

QLBs are more effective at alleviating pain in patients undergoing laparoscopic renal surgery, which is beneficial for reducing the use of opioids, alleviating adverse reactions, improving the quality of recovery.

## Full-text entities

- **Diseases:** pain (MESH:D010146), nausea and vomiting (MESH:D020250)
- **Chemicals:** QLB (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12335789