# Effects of Intratympanic Steroid Therapy in Sudden Hearing Loss in Children: The Clinical Case of an Exceptionally Late Hearing Recovery

**Authors:** Marco Capelli

PMC · DOI: 10.22038/ijorl.2025.83020.3794 · Iranian Journal of Otorhinolaryngology · 2025-01-01

## TL;DR

A 15-year-old child with sudden hearing loss recovered after intratympanic steroid injections, suggesting this treatment could be effective even weeks after symptoms begin.

## Contribution

Demonstrates the potential efficacy of intratympanic steroids as a first-line treatment for sudden hearing loss in children.

## Key findings

- The patient showed unexpected hearing recovery after intratympanic methylprednisolone injections.
- Intratympanic steroids may be effective even weeks after symptom onset in pediatric sudden hearing loss.
- This treatment has minimal systemic side effects, making it suitable for children.

## Abstract

Sudden hearing loss represents a medical emergency that can potentially have a highly negative impact on an individual's quality of life. In particular it can represent a serious concern in pediatric age, interfering cognitive and language development. Despite the seriousness of the problem, there is currently no consensus on diagnostic and therapeutic management methods, and the debate is still open.

We present the case of a 15-year-old child with a sudden right-sided hearing loss of profound degree and of idiopathic etiology. Initially he was treated with oral steroid treatment and subsequently to multiple sessions of hyperbaric oxygen therapy without satisfactory results. Several weeks after the onset of symptoms, the patient underwent a cycle of 3 intratympanic methylprednisolone injections with unexpected hearing recovery.

Intratympanic steroid therapy could represent not only a life-saving therapeutic choice as it is currently considered, but also a first therapeutic choice, particularly in pediatric age, thanks to substantial absence of systemic side effects and the potential efficacy even after many weeks from the onset of symptoms.

## Linked entities

- **Chemicals:** methylprednisolone (PubChem CID 6741)
- **Diseases:** sudden hearing loss (MONDO:0043373)

## Full-text entities

- **Diseases:** hearing loss (MESH:D034381), Sudden Hearing Loss (MESH:D003639)
- **Chemicals:** Steroid (MESH:D013256), methylprednisolone (MESH:D008775), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12335661/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12335661/full.md

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Source: https://tomesphere.com/paper/PMC12335661