# Abdominal Necrotizing Fasciitis Secondary to the Intramuscular Injection of Permethrin: An Uncommon Case Presentation

**Authors:** Juan M Gómez-Rodríguez, Jorge L Estévez-Arrizon, Luis E Ocampo-Guzmán, Oquitzin Flores-Palomares

PMC · DOI: 10.7759/cureus.89524 · Cureus · 2025-08-06

## TL;DR

A woman developed a severe abdominal infection after injecting permethrin, highlighting the dangers of toxic substance misuse.

## Contribution

This case report highlights the rare but severe complication of necrotizing fasciitis following intramuscular permethrin injection.

## Key findings

- The patient developed necrotizing fasciitis after intramuscular permethrin injection.
- Surgical debridement and antibiotics led to a favorable outcome.
- Permethrin was linked to local tissue toxicity and infection.

## Abstract

Necrotizing fasciitis is a severe, rapidly progressing bacterial infection. We report a unique case in a 40-year-old woman with schizophrenia who developed necrotizing fasciitis after self-injecting permethrin intramuscularly into the lower abdomen. The patient presented with abdominal pain, fever, and a fluid collection on computed tomography. Surgical debridement and antibiotic therapy were performed, resulting in a favorable clinical evolution. The case suggests that permethrin induced local toxicity and tissue damage. Early diagnosis, prompt surgical intervention, and prevention of toxic substance misuse are essential.

## Linked entities

- **Chemicals:** permethrin (PubChem CID 40326)
- **Diseases:** necrotizing fasciitis (MONDO:0004835), schizophrenia (MONDO:0005090)

## Full-text entities

- **Diseases:** fever (MESH:D005334), tissue damage (MESH:D017695), toxic substance misuse (MESH:D065606), toxicity (MESH:D064420), Abdominal Necrotizing Fasciitis (MESH:D019115), schizophrenia (MESH:D012559), abdominal pain (MESH:D015746), bacterial infection (MESH:D001424)
- **Chemicals:** Permethrin (MESH:D026023)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12335332/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12335332/full.md

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Source: https://tomesphere.com/paper/PMC12335332