# Hemoadsorption as Adjunctive Therapy in Streptococcal Toxic Shock Syndrome

## TL;DR

This paper reports a case where hemoadsorption helped treat a severe streptococcal infection, leading to recovery by reducing inflammation.

## Contribution

The paper presents a novel case of using hemoadsorption as an adjunctive therapy for streptococcal toxic shock syndrome.

## Key findings

- The patient showed progressive clinical improvement after hemoadsorption treatment.
- Hemoadsorption may reduce circulating inflammatory mediators in septic shock.
- The patient fully recovered following the combined treatment approach.

## Abstract

Group A Streptococcus (GAS) is a Gram-positive bacterium that can lead to invasive infections, such as necrotizing fasciitis or streptococcal toxic shock syndrome (STSS), a condition associated with high morbidity and mortality rates. We report the case of a 70-year-old male admitted to the intensive care unit with septic shock and multiorgan failure due to GAS bacteremia. The patient was treated with broad-spectrum antibiotics, intravenous immunoglobulin, and organ support measures, including vasopressors, renal replacement therapy, and hemoadsorption using the Jafron HA380 cartridge. This approach led to progressive clinical improvement and a full recovery. Hemoadsorption may have contributed to the resolution of shock by reducing circulating inflammatory mediators. This case supports its potential as an adjunctive treatment in STSS.