# Fibroids in Pregnancy: A Case Series

**Authors:** Sofia Amber, Asma Fahad, Sadia Maqbool, Nighat Aftab, Saima Faraz

PMC · DOI: 10.7759/cureus.87577 · Cureus · 2025-07-09

## TL;DR

This case series examines how uterine fibroids during pregnancy affect maternal and neonatal outcomes, emphasizing the need for careful monitoring and individualized care.

## Contribution

The study provides clinical insights into pregnancy outcomes associated with fibroid location and size through a case series approach.

## Key findings

- All deliveries occurred via cesarean section between 35 and 36 weeks due to fibroid complications.
- Neonates required NICU admission for respiratory distress, but no birth asphyxia was observed.
- Cervical fibroids caused intraoperative difficulties, highlighting the importance of individualized delivery planning.

## Abstract

Uterine fibroids are common benign tumors that can complicate pregnancy by affecting maternal and fetal outcomes. The impact depends on fibroid size, number, and location. This case series aims to highlight clinical outcomes in pregnancies complicated by fibroids. Three pregnant women with known uterine fibroids were followed through antenatal, intrapartum, and postpartum periods at a tertiary care hospital. Maternal demographics, fibroid characteristics, pregnancy complications, mode of delivery, and neonatal outcomes were reviewed. All patients conceived spontaneously and were diagnosed with fibroids between early pregnancy and the second trimester. Fibroid sites included the cervix, anterior lower uterine segment, and anterior/posterior subserosal regions, with sizes ranging from 4.4×4.5 cm to 12×11.2 cm. All deliveries were conducted by lower-segment cesarean section between 35 and 36 weeks of gestation. Two neonates required NICU admission for respiratory distress, though no cases of birth asphyxia were reported. Intraoperative difficulties were encountered mainly in cases with cervical fibroids. Maternal outcomes were favorable with no major postoperative complications. It is concluded that fibroids in pregnancy, particularly those that are large or lower-segment located, increase the risk of preterm birth and cesarean delivery. Careful antenatal monitoring and individualized delivery planning are essential to optimize maternal and neonatal outcomes.

## Linked entities

- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** birth asphyxia (MESH:D001237), Fibroid (MESH:D007889), respiratory distress (MESH:D012128), benign tumors (MESH:D009369), preterm birth (MESH:D047928)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12334970/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12334970/full.md

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Source: https://tomesphere.com/paper/PMC12334970