# The Systematic Comparison of Enhancer of Zeste Homolog‐2‐, Bromodomain‐containing Proteins‐, Histone Deacetylase‐, and DNA‐methyltransferase 1‐inhibitors in a Syngeneic Murine Model of Melanoma Reveals Differential Anti‐tumoral and Immunomodulatory Activities

**Authors:** Valentina Rigo, Adriana Amaro, Francesco Reggiani, Daniela Fenoglio, Stefania Martini, Tiziana Altosole, Mariangela Petito, Cecilia Profumo, Michela Croce

PMC · DOI: 10.1002/mco2.70336 · MedComm · 2025-08-09

## Full-text entities

- **Genes:** Ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit) [NCBI Gene 14056] {aka Enx-1, Enx1h, KMT6, mKIAA4065}
- **Diseases:** Melanoma (MESH:D008545)
- **Species:** Mus musculus (house mouse, species) [taxon 10090]

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Source: https://tomesphere.com/paper/PMC12334842