# Metastatic Melanoma to the Stomach: A Rare Case of Tumor Burden Beyond the Skin

**Authors:** Akhil Adla, Rahul Reddy Tirumalareddy, Peter Snell

PMC · DOI: 10.7759/cureus.87636 · Cureus · 2025-07-09

## TL;DR

This paper presents a rare case of metastatic melanoma spreading to the stomach, emphasizing diagnostic challenges and treatment considerations.

## Contribution

The novelty lies in documenting a rare metastatic melanoma case to the stomach with nonspecific symptoms and highlighting diagnostic and prognostic implications.

## Key findings

- Metastatic melanoma to the stomach is rare and often presents with nonspecific gastrointestinal symptoms.
- Proper biopsy staining is crucial for accurate diagnosis of metastatic melanoma in unusual locations.
- Long-term surveillance is essential for managing recurring metastatic melanoma.

## Abstract

Metastatic melanoma is a rare occurrence and is a challenge to diagnose based on the location of spread. The increased incidence in the United States (US) can be attributed to the popularity of tanning beds, an aging population, climate change, public awareness, and better diagnostic tools. Despite the large number of melanoma cases, five-year survival rates remain high; however, survival rates dramatically change with metastatic disease. Melanoma commonly spreads to other skin sites, lymph nodes, the liver, bones, and the brain. We present a rare instance of metastatic melanoma in the stomach in an 81-year-old male patient with nonspecific gastrointestinal (GI) symptoms, including five years of dysphagia, weight loss, and coughing spells. This case discusses the prognostic implications of metastatic disease, the importance of proper staining with biopsy samples, treatment, and highlights the importance of recurring disease surveillance.

## Linked entities

- **Diseases:** melanoma (MONDO:0005105), metastatic melanoma (MONDO:0005191)

## Full-text entities

- **Diseases:** metastatic (MESH:D000092182), dysphagia (MESH:D003680), gastrointestinal (GI) symptoms (MESH:D012817), Tumor (MESH:D009369), weight loss (MESH:D015431), Melanoma (MESH:D008545), coughing spells (MESH:D003371)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12334763/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12334763/full.md

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Source: https://tomesphere.com/paper/PMC12334763