# Lymphoedema - Filariasis or soft tissue sarcoma? A case report

**Authors:** Tamring Sarinah, Mat Nawi Zanaridah, Nik Yusof Fuad Nik Farah, Joon Hi Tham, Mohamad Setia Awang Shahrunizam

PMC · DOI: 10.51866/cr.877 · Malaysian Family Physician : the Official Journal of the Academy of Family Physicians of Malaysia · 2025-07-29

## TL;DR

A man with leg swelling and a mass was diagnosed with soft tissue sarcoma after considering lymphatic filariasis due to travel history.

## Contribution

Highlights the importance of considering rare conditions like soft tissue sarcoma in differential diagnosis of limb swelling.

## Key findings

- Magnetic resonance imaging and histopathology confirmed pleomorphic dermal sarcoma.
- Lymphatic filariasis was ruled out despite relevant travel history.
- Multidisciplinary team involvement is crucial for managing such complex cases.

## Abstract

This is a case report of a middle-aged man who presented with chronic unilateral lower limb swelling and a mass on the same side. Several important differential diagnoses were considered. Lymphatic filariasis was included in the differential diagnoses due to a history of travel to a district endemic with filariasis in Sabah. A final diagnosis of soft tissue sarcoma was provisionally made based on the magnetic resonance imaging findings and confirmed by histopathological examination as pleomorphic dermal sarcoma. Both conditions are unusual but important causes in primary care due to their association with poor morbidity and risk of mortality. Patient management should involve a multidisciplinary team, including primary care, public health, radiology, pathology and orthopaedics.

## Linked entities

- **Diseases:** soft tissue sarcoma (MONDO:0018078)

## Full-text entities

- **Diseases:** pleomorphic dermal sarcoma (MESH:D012509), Lymphatic filariasis (MESH:D004605), Lymphoedema - Filariasis (MESH:D005368), swelling (MESH:D004487)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12334323/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12334323/full.md

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Source: https://tomesphere.com/paper/PMC12334323