This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTION: “Mechanical stretch promotes antioxidant responses and cardiomyogenic differentiation in P19 cells”
Journal of Tissue Engineering and Regenerative Medicine

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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TopicsExercise and Physiological Responses · Adipose Tissue and Metabolism · Sirtuins and Resveratrol in Medicine
RETRACTION: J. Cheng, Q. Zou, Y. Xue, C. Sun, and D. Zhang, “Mechanical stretch promotes antioxidant responses and cardiomyogenic differentiation in P19 cells,” Journal of Tissue Engineering and Regenerative Medicine, 2021 (2021): term.3184, https://doi.org/10.1002/term.3184.
The above article, published online on 20 March 2021 in Wiley Online Library (https://wileyonlinelibrary.com), has been retracted following the agreement of the journal's Chief Editor Catherine Kuo; and John Wiley & Sons Ltd.
The retraction has been agreed following an investigation of the concerns raised by Hoya Camphorifolia on PubPeer [1], which identified concerns regarding Figures 4 and 5.
Specifically, similarity has been identified between the Western blot bands corresponding to SIRT 1 and GAPDH in Figure 4(b) to c-Casp 3 and c-Casp 9 bands in Figure 3(d) of [2]. Unexpected similarities were also identified between the cTNT and Cx43 bands in Figures 5(b), 5(d) and the Bcl-2 and Bad blots in Figure 3(d) of [2].
As a result of the investigation, the data and conclusions of this article are considered unreliable.
The authors were informed of the decision to retract the article but did not provide a response.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Hoya camphorifolia Mechanical stretch promotes antioxidant responses and cardiomyogenic differentiation in P 19 cells Pub Peer 2023 May https://pubpeer.com/publications/C 460FF 399FE 8F 2683 DA 88EC 7378524 10.1002/term.318433743188 · doi ↗ · pubmed ↗
- 2Liu H. Zhao J. Fu R. Zhu C. Fan D. The ginsenoside Rk 3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI 3K/Akt/m TOR pathway P Lo S One 2019145 p. e 021675910.1371/journal.pone.02167592-s 2.0-85065910428 PMC 651982131091245 · doi ↗ · pubmed ↗
