# Right Ventricular Outflow Tract Mass in Antiphospholipid Syndrome

**Authors:** Mohammad Sahebjam, Hamidreza Poorhosseini, Arezoo Haji Ali, Tayyebe Mohammad Gholizad, Saba Mohammadzadeh

PMC · DOI: 10.1002/ccr3.70784 · Clinical Case Reports · 2025-08-08

## TL;DR

A rare case of thrombosis in the right ventricular outflow tract in a patient with antiphospholipid syndrome is described, showing regression with anticoagulation.

## Contribution

Reports a rare manifestation of APS involving the RVOT and demonstrates successful treatment with anticoagulation.

## Key findings

- A thrombosis in the right ventricular outflow tract was identified in a 49-year-old APS patient.
- Aggressive anticoagulation led to regression of the thrombosis within one month.
- Transthoracic echocardiography confirmed the presence and regression of the mass.

## Abstract

Antiphospholipid syndrome (APS) is well known for its association with arterial and venous thrombosis. Intracardiac thrombosis—more often involving the right atrium—is a serious manifestation of the disease. We describe an APS case with a thrombosis in the right ventricular outflow tract (RVOT), which underwent regression after aggressive anticoagulation.

We represent a 49‐year‐old man with APS syndrome and history of multiple arterial and venous thrombosis, who presented with dyspnea. Transthoracic echocardiography revealed a mobile, round‐shaped, non‐homogeneous mass (14 × 8 mm), attached to RVOT, in favor of thrombosis. With aggressive anticoagulation the thrombosis regressed after about 1 month.

## Linked entities

- **Diseases:** Antiphospholipid syndrome (MONDO:0017278), thrombosis (MONDO:0000831)

## Full-text entities

- **Diseases:** thrombosis (MESH:D013927), arterial and venous thrombosis (MESH:D020246), APS (MESH:D016736)

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12334272/full.md

## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12334272/full.md

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Source: https://tomesphere.com/paper/PMC12334272