# Central Odontogenic Fibroma: A Rare Benign Tumor With Potentially Life‐Threatening Implications

**Authors:** Farhad Ghorbani, Jamaledin Motazedian, Mohammad Saleh Khaghaninejad, Haleh Keshvari, Maryam Paknahad

PMC · DOI: 10.1002/ccr3.70761 · Clinical Case Reports · 2025-08-08

## TL;DR

Central odontogenic fibroma is a rare benign tumor that can cause serious health issues if not treated.

## Contribution

Highlights the potentially life-threatening implications of a typically benign and slow-growing tumor.

## Key findings

- COF can lead to tooth displacement and bone destruction.
- Neglecting COF may result in life-threatening airway obstruction.

## Abstract

Central odontogenic fibroma (COF) is a rare benign tumor originating from periodontal tissues. Although it typically grows slowly and remains asymptomatic, COF can cause significant complications when neglected, including displacement of teeth, bone destruction, and even life‐threatening airway obstruction.

## Full-text entities

- **Diseases:** Benign Tumor (MESH:D009369), bone destruction (MESH:D001847), airway obstruction (MESH:D000402), COF (MESH:D005350), displacement of teeth (MESH:D018677)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12334270/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12334270/full.md

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Source: https://tomesphere.com/paper/PMC12334270