# ASCL1 regulates and cooperates with FOXA2 to drive terminal neuroendocrine phenotype in prostate cancer

**Authors:** Shaghayegh Nouruzi, Takeshi Namekawa, Nakisa Tabrizian, Maxim Kobelev, Olena Sivak, Joshua M Scurll, Cassandra Jingjing Cui, Dwaipayan Ganguli, Amina Zoubeidi

PMC · DOI: 10.1172/jci.insight.196861 · JCI Insight · 2025-08-08

## Full-text entities

- **Genes:** ASCL1 (achaete-scute family bHLH transcription factor 1) [NCBI Gene 429] {aka ASH1, HASH1, MASH1, bHLHa46}, FOXA2 (forkhead box A2) [NCBI Gene 3170] {aka HNF-3-beta, HNF3B, TCF3B}
- **Diseases:** prostate cancer (MESH:D011471)

## Full text

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Source: https://tomesphere.com/paper/PMC12333938