# Gallbladder schistosomiasis as an uncommon cause of recurrent cholecystitis

**Authors:** Seid Getahun Abdela, Suleiman Ayalew Belay, Abdu Assen Ahmed

PMC · DOI: 10.1016/j.idcr.2025.e02331 · IDCases · 2025-07-27

## TL;DR

A rare case of gallbladder schistosomiasis caused recurrent cholecystitis in a young woman from Ethiopia, confirmed by histopathology and successfully treated with praziquantel.

## Contribution

This case highlights gallbladder schistosomiasis as an uncommon cause of recurrent cholecystitis that may be overlooked clinically.

## Key findings

- Histopathology confirmed granulomatous inflammation and calcified Schistosoma mansoni ova in the gallbladder wall.
- The patient fully recovered after treatment with praziquantel.
- Gallbladder schistosomiasis is rare and often overshadowed by more common manifestations of the infection.

## Abstract

Gallbladder schistosomiasis is an extremely rare manifestation of Schistosoma mansoni infection, typically overshadowed by hepatic, intestinal, or urogenital involvement. We report a case of a 28-year-old woman from Ethiopia with a two-year history of recurrent right upper quadrant abdominal pain. Ultrasound suggested acalculous cholecystitis with a possible gallbladder polyp, and she underwent elective open cholecystectomy. Histopathology confirmed the presence of granulomatous inflammation and calcified Schistosoma mansoni ova embedded in the gallbladder wall. The patient recovered fully following praziquantel therapy.

## Linked entities

- **Chemicals:** praziquantel (PubChem CID 4891)
- **Diseases:** Schistosoma mansoni infection (MONDO:0044345)
- **Species:** Schistosoma mansoni (taxon 6183)

## Full-text entities

- **Diseases:** abdominal pain (MESH:D015746), cholecystitis (MESH:D002764), Schistosoma mansoni infection (MESH:D012555), gallbladder polyp (MESH:D011127), granulomatous inflammation (MESH:D007249), Gallbladder schistosomiasis (MESH:D012552), acalculous cholecystitis (MESH:D042101)
- **Chemicals:** praziquantel (MESH:D011223)
- **Species:** Schistosoma mansoni (species) [taxon 6183], Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12332869/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12332869/full.md

## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12332869/full.md

---
Source: https://tomesphere.com/paper/PMC12332869