# Treatment of blood blister-like aneurysms of the supraclinoid internal carotid artery using pipeline and lattice flow diverters and coiling

**Authors:** Xuan Chen, Zibo Zhou, Jinguang Gao, Jinlu Yu

PMC · DOI: 10.3389/fneur.2025.1607683 · Frontiers in Neurology · 2025-07-25

## TL;DR

This paper reports on the treatment of blood blister-like aneurysms in the brain using flow diverters and coiling, showing good outcomes but highlighting risks of ischemic complications.

## Contribution

The study presents a case series demonstrating the effectiveness of combined flow diverter and coiling techniques for treating BBAs.

## Key findings

- All 13 aneurysms were cured with successful repair of the internal carotid artery.
- Ischemic complications occurred in some patients, including one death and severe disability.
- Most patients had favorable outcomes with modified Rankin Scale scores of 0 or 1 at six months.

## Abstract

Flow diverters (FDs) have shown the potential to treat blood blister-like aneurysms (BBAs) of the supraclinoid internal carotid artery (ICA). We report a series of cases treated by both deploying FDs and coiling.

Based on the Bojanowski classification, the BBAs of the supraclinoid ICA were classified into types I–IV. Based on the approach used for endovascular treatment (EVT) of the BBAs, the EVTs were categorized into types 1–3. The modified Rankin scale (mRS) was used to assess the clinical follow-up outcome.

Thirteen patients with 13 BBAs of the supraclinoid ICA who were aged 22–66 (49.8 ± 13.5) years were included. There were 12 females and 1 male. All patients had experienced subarachnoid hemorrhage. According to the Bojanowski’s et al. classification, a total of 2, 7, 3, and 1 BBAs were categorized as types I, II, III, and IV, respectively. Preoperative vasospasms were detected in 4 patients. EVT types 1, 2, and 3 were used to treat 4, 7, and 2 BBAs, respectively. After EVT, 2 patients with preoperative vasospasm experienced hemiparesis but later recovered. One patient with a preoperative vasospasm experienced multiple infarctions and died. One patient who discontinued antiplatelet therapy experienced multiple infarctions and suffered severe disability. ‌Twelve patients completed a post-EVT six-month follow-up, excluding the one with postoperative mortality.‌ The mRS scores were 0, 1, and 4 for 10, 1, and 1 patients, respectively. Eleven patients were subjected to angiographic follow-up. All BBAs were cured, and the supraclinoid ICAs were repaired.

For patients with BBAs, deploying an FD and coiling can yield good outcomes. However, ischemic complications should not be overlooked.

## Linked entities

- **Diseases:** subarachnoid hemorrhage (MONDO:0005099)

## Full-text entities

- **Diseases:** vasospasm (MESH:D020301), subarachnoid hemorrhage (MESH:D013345), ischemic (MESH:D002545), BBAs (MESH:D001768), hemiparesis (MESH:D010291), infarctions (MESH:D007238)
- **Chemicals:** antiplatelet (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12331767/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12331767/full.md

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Source: https://tomesphere.com/paper/PMC12331767