# Modeled Carbon Footprint of Change of Sterile Gloves and Instruments for Abdominal Wound Closure

**Authors:** Virginia Ledda, Adesoji Ademuyiwa, Adewale Adisa, Aneel Bhangu, Dhruv Ghosh, Parvez David Haque, J. C. Allen Ingabire, Faustin Ntirenganya, Maria Picciochi, Atul Suroy, Robert Lillywhite, Dmitri Nepogodiev

PMC · DOI: 10.1001/jamanetworkopen.2025.25355 · 2025-08-06

## TL;DR

Changing sterile gloves and instruments before closing abdominal wounds reduces carbon emissions, especially in low- and middle-income countries.

## Contribution

A decision analytic model quantifies the carbon footprint reduction of changing gloves and instruments in abdominal surgeries.

## Key findings

- Changing gloves and instruments reduced carbon footprint by 10.97 kgCO2e in clean-contaminated surgeries in lower- and middle-income countries.
- In high-income countries, the reduction was 4.14 kgCO2e for clean-contaminated surgeries.
- The intervention consistently lowered carbon emissions across all country income levels.

## Abstract

What is the global carbon footprint of changing sterile gloves and instruments before closure of clean-contaminated and contaminated-dirty abdominal wounds?

This decision analytic model showed that, in the base case scenario in lower- and middle-income countries, changing gloves and instruments was associated with a reduction in the wound-specific carbon footprint of 10.97 kg CO2 equivalents (kgCO2e) in clean-contaminated surgeries and of 22.60 kgCO2e in contaminated-dirty surgeries. In high-income countries in the best-case scenario, reductions were 4.14 kgCO2e and 10.48 kgCO2e, respectively.

This model demonstrates an overall net reduction in carbon emissions with the change of sterile gloves and instruments, supporting its adoption in surgical practice.

This decision analytical model study evaluates the association of changing sterilized gloves and instruments in surgery with changes in wound care–specific global carbon footprint.

The Cheetah randomized trial demonstrated that changing sterile gloves and instruments before wound closure reduces surgical site infections (SSI) in abdominal surgery. However, its environmental impact remains unclear.

To estimate the global carbon footprint associated with changing sterile gloves and instruments before closure abdominal wound.

This decision analytic model compared the carbon footprint of a glove and instrument change intervention against a control (no glove and instrument change). Model parameters were sourced from a large cluster randomized trial conducted in 7 low- and middle-income countries (LMICs) between June 2020 and March 2022, as well as data from stakeholder engagement and existing research. Boundaries included the trial intervention and in-hospital resources used to manage SSI. The analysis was stratified by wound contamination status (clean-contaminated, contaminated-dirty) and country-income classification.

Average per-patient wound-specific carbon footprint, calculated as the sum of the carbon footprint of glove and instrument change and SSI. Sensitivity analyses were based on the lowest and highest possible values for key model parameters: intervention effectiveness, intervention carbon footprint, and SSI carbon footprint. The best-case analysis was based on highest possible intervention effectiveness, lowest possible intervention carbon footprint, highest possible SSI carbon footprint. The worst-case analysis was based on lowest intervention effectiveness, highest intervention carbon footprint, and lowest SSI carbon footprint.

In LMICs, the difference in carbon footprints between the intervention and control groups was 10.97 kg CO2 equivalents (kgCO2e) (scenario range, −2.53 to 33.50 kgCO2e) for clean-contaminated and 22.60 kgCO2e (scenario range, −1.62 to 61.17 kgCO2e) for contaminated-dirty surgeries. In high-income countries, differences were 4.14 kgCO2e (scenario range, −3.38 to 17.95 kgCO2e) and 10.48 kgCO2e (scenario range, −3.06 to 37.62 kgCO2e), respectively. Country-level modeling found the intervention to be consistently associated with a lower wound-specific carbon footprint across all countries.

In this decision analytic model, sterile glove and instrument change before wound closure was associated with a reduced wound-specific carbon footprint across all country income settings. Alongside clinical and economic benefits, this intervention may support more sustainable surgical care; national associations and governments should consider its adoption to improve outcomes for both patients and the planet.

## Full-text entities

- **Diseases:** infections (MESH:D007239), SSI (MESH:D013530)
- **Chemicals:** Carbon (MESH:D002244), CO2 (MESH:D002245)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12329605/full.md

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Source: https://tomesphere.com/paper/PMC12329605