Vaginal group B Streptococcus colonization among pregnant women in Ethiopia: Prevalence, risk factors, and antimicrobial susceptibility

TL;DR

A study in Ethiopia found a 13% rate of vaginal Group B Streptococcus colonization in pregnant women, with higher rates in those who had given birth before and antibiotic resistance in some cases.

Contribution

This study provides new data on GBS prevalence, risk factors, and antimicrobial resistance in pregnant women in Jimma, Ethiopia.

Findings

Vaginal GBS colonization rate was 13% among 200 pregnant women in Jimma, Ethiopia.

Multigravida women had a higher colonization rate (17%) compared to primigravida women (3.4%).

GBS isolates showed resistance to ampicillin, penicillin, and clindamycin.

Abstract

Group B Streptococcus (GBS) colonization during pregnancy poses significant public health risks, contributing to adverse outcomes like neonatal septicemia, meningitis, and pneumonia. Transmission from mother to newborn during delivery is common. In Jimma, Ethiopia, limited data exist on GBS prevalence, risk factors, and antimicrobial resistance among pregnant women, with no universal screening protocol to mitigate neonatal infections.

This study assessed GBS prevalence, antimicrobial susceptibility, and associated risk factors among 200 pregnant women at Jimma University Hospital. Vaginal swabs collected at 35–37 weeks gestation were cultured and tested for GBS using standard methods.

Results showed a colonization rate of 13% (26/200), higher in multigravida (17%) compared to primigravida (3.4%). Resistance rates to ampicillin, penicillin, clindamycin, and erythromycin were 30.8%, 23.1%, 19.2%, and 15.4%, respectively.

The findings underscore the importance of routine screening and susceptibility testing to inform prophylactic strategies and curb neonatal infections.

•Vaginal GBS colonization in Jimma, Ethiopia was 13% (26 of 200 women tested)•GBS more common in multigravida (17%) than in primigravida women (3.4%)•GBS isolates showed resistance to ampicillin, penicillin, and clindamycin•Screening and susceptibility testing for GBS is key to proper prophylaxis

Vaginal GBS colonization in Jimma, Ethiopia was 13% (26 of 200 women tested)

GBS more common in multigravida (17%) than in primigravida women (3.4%)

GBS isolates showed resistance to ampicillin, penicillin, and clindamycin

Screening and susceptibility testing for GBS is key to proper prophylaxis

Medical microbiology; Women’s health

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