# Combination of mechanical debridement and interleukin 12 or interleukin 23 therapy for refractory facial pyoderma gangrenosum with NOD2 mutation

**Authors:** Morgan Vague, Moira Shea, Shivani Thacker, Heather Onoday, Alex G. Ortega Loayza

PMC · DOI: 10.1016/j.jdcr.2025.06.019 · 2025-06-23

## Full-text entities

- **Genes:** NOD2 (nucleotide binding oligomerization domain containing 2) [NCBI Gene 64127] {aka ACUG, BLAU, BLAUS, CARD15, CD, CLR16.3}, IL37 (interleukin 37) [NCBI Gene 27178] {aka FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H, IL-1H4}, IL12B (interleukin 12B) [NCBI Gene 3593] {aka CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF}
- **Diseases:** pyoderma gangrenosum (MESH:D017511)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12328780/full.md

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Source: https://tomesphere.com/paper/PMC12328780