# Novel atypical G protein-coupled receptor (GPCR)-arrestin complexes: a structural snapshot of the barcode hypothesis

**Authors:** Jenny C. Filor, Edda S. F. Matthees, Carsten Hoffmann

PMC · DOI: 10.1038/s41392-025-02338-0 · 2025-08-07

## Full-text entities

- **Genes:** GCGR (glucagon receptor) [NCBI Gene 2642] {aka GGR, GL-R, MVAH}, GRK2 (G protein-coupled receptor kinase 2) [NCBI Gene 156] {aka ADRBK1, BARK1, BETA-ARK1}, ARRB1 (arrestin beta 1) [NCBI Gene 408] {aka ARB1, ARR1}, ACKR3 (atypical chemokine receptor 3) [NCBI Gene 57007] {aka CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1}, GRK5 (G protein-coupled receptor kinase 5) [NCBI Gene 2869] {aka FP2025, GPRK5}, CXCR4 (C-X-C motif chemokine receptor 4) [NCBI Gene 7852] {aka CD184, D2S201E, FB22, HM89, HSY3RR, LCR1}, OXER1 (oxoeicosanoid receptor 1) [NCBI Gene 165140] {aka GPCR, GPR170, TG1019}, ARR3 (arrestin 3) [NCBI Gene 407] {aka ARRX, MYP26, cArr}, ARRB2 (arrestin beta 2) [NCBI Gene 409] {aka ARB2, ARR2, BARR2}, CXCR3 (C-X-C motif chemokine receptor 3) [NCBI Gene 2833] {aka CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R}
- **Chemicals:** lipids (MESH:D008055), CXCL12LRHQ (-)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12328772/full.md

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Source: https://tomesphere.com/paper/PMC12328772