# Review on Icariin as A Novel Medicaments to Confront Ovarian Cancer: Role of Icariin Against Ovarian Cancer

## TL;DR

This paper reviews how icariin, a plant compound, may help treat ovarian cancer by targeting harmful molecular pathways.

## Contribution

The paper highlights icariin's novel potential as a safe and effective treatment for ovarian cancer.

## Key findings

- Icariin shows antitumor effects against ovarian cancer.
- Icariin modulates altered molecular signaling pathways in ovarian cancer.
- Icariin may offer a safer alternative to current therapies with fewer side effects.

## Abstract

Ovarian cancer is described as one of the most common types of cancer and the
leading cause of cancer-related deaths due to the high aggressiveness of this
malignancy. However, the current therapeutically strategies failed to confront
ovarian cancer or are accompanied by significant adverse effects leading to the
recurrence of the disease and/or affecting the quality of life of survivors. On
the other hand, ovarian cancer is recognized as a heterogenous disorder that is
specified by alteration in a variety of molecular and cellular markers. Thereby,
researchers are keen to find a novel therapeutical strategy representing high
efficacy and safety, as well as be able to modulate altered biomolecules and
signaling pathways. Icariin is a phytoestrogen with desired properties that are
suggested for several chronic complications, particularly different types of
cancer. The aim of the present study was to reveal the ameliorative
characteristics of icariin and then discuss the antitumoral activities of this
phytochemical against ovarian cancer with an emphasis on the modified molecular
signaling pathways.