# Umbilical Endometriosis With Appendiceal Involvement: A Case Report

**Authors:** Varna Jammula, Kevin Johnson, Matthew Grolle

PMC · DOI: 10.7759/cureus.87473 · Cureus · 2025-07-07

## TL;DR

A 29-year-old woman presented with rare umbilical and appendiceal endometriosis, diagnosed through laparoscopy and confirmed by pathology.

## Contribution

This case report highlights the rare coexistence of umbilical and appendiceal endometriosis.

## Key findings

- The patient had a periumbilical mass that bled during menstruation and was diagnosed with stage IV endometriosis.
- An incidental appendiceal mass was found and confirmed to be endometriosis via pathology.
- Postoperative recovery was uneventful, emphasizing the importance of early diagnosis and laparoscopic intervention.

## Abstract

Endometriosis is a common disease that affects women worldwide. While it is most commonly located in the pelvis, lesions may occur in other areas of the body. Concurrent umbilical and appendiceal endometriosis is rare. We present a case of umbilical endometriosis with appendiceal involvement in a 29-year-old female. The patient presented with a periumbilical mass that bled during her menstrual cycle. She also reported lower quadrant pelvic pain, dysmenorrhea, and dyspareunia. Imaging revealed an umbilical hernia and a lesion abutting the suspensory ligament of the right ovary. Cancer antigen-125 (CA-125) levels were elevated. Diagnostic laparoscopy revealed stage IV endometriosis with severe adhesions to the uterus, posterior cul-de-sac, descending and sigmoid colon, and bladder. An incidental appendiceal mass was noted, resulting in an appendectomy. The periumbilical mass was removed. Pathology revealed umbilical and appendiceal endometriosis. There were no complications in the postoperative period. The diverse manifestations of endometriosis emphasize the importance of considering extrapelvic involvement, especially in patients with atypical dermatological symptoms. Early recognition and subsequent laparoscopy for both the diagnosis and treatment of endometriosis are essential for successful patient management.

## Linked entities

- **Diseases:** endometriosis (MONDO:0005133)

## Full-text entities

- **Genes:** MUC16 (mucin 16, cell surface associated) [NCBI Gene 94025] {aka CA125}
- **Diseases:** dysmenorrhea (MESH:D004412), adhesions (MESH:D000267), Endometriosis (MESH:D004715), pelvic pain (MESH:D017699), dyspareunia (MESH:D004414), umbilical hernia (MESH:D006554), stage IV (MESH:D062706)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12327966/full.md

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Source: https://tomesphere.com/paper/PMC12327966