# Editorial: Novel therapeutic targets for lower urinary tract symptoms

**Authors:** Jianshu Ni, Baojun Gu, Naoki Yoshimura

PMC · DOI: 10.3389/fruro.2023.1239287 · Frontiers in Urology · 2023-06-26

## Full-text entities

- **Genes:** MAPK8 (mitogen-activated protein kinase 8) [NCBI Gene 5599] {aka JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8}, NGF (nerve growth factor) [NCBI Gene 4803] {aka Beta-NGF, HSAN5, NGFB}, Bdnf (brain derived neurotrophic factor) [NCBI Gene 12064], RHO (rhodopsin) [NCBI Gene 6010] {aka CSNBAD1, OPN2, RP4}, NGFR (nerve growth factor receptor) [NCBI Gene 4804] {aka CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR}, Trpv1 (transient receptor potential cation channel, subfamily V, member 1) [NCBI Gene 193034] {aka OTRPC1, TRPV1alpha, TRPV1beta, VR-1, Vr1}, NTRK2 (neurotrophic receptor tyrosine kinase 2) [NCBI Gene 4915] {aka DEE58, EIEE58, GP145-TrkB, OBHD, TRKB, trk-B}, Il6 (interleukin 6) [NCBI Gene 16193] {aka Il-6}, NTRK1 (neurotrophic receptor tyrosine kinase 1) [NCBI Gene 4914] {aka MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA}, Ngf (nerve growth factor) [NCBI Gene 18049] {aka Ngfb, beta-NGF}, Trpv4 (transient receptor potential cation channel, subfamily V, member 4) [NCBI Gene 63873] {aka 0610033B08Rik, OTRPC4, Trp12, VR-OAC, VRL-2, VROAC}
- **Diseases:** polyneuropathy (MESH:D011115), pelvic pain (MESH:D017699), pain syndromes (MESH:C538101), SFPN (MESH:D000071075), IC/BPS (MESH:C537984), cystitis (MESH:D003556), BPH (MESH:D011470), DO (MESH:D053201), bladder disorders (MESH:D001745), BOO (MESH:D001748), inflammatory (MESH:D007249), chronic pain disorders (MESH:D059350), anxiety (MESH:D001007), Interstitial cystitis/bladder pain syndrome (MESH:D018856), voiding dysfunction (MESH:C537271)
- **Chemicals:** CYP (MESH:D003520)
- **Species:** Homo sapiens (human, species) [taxon 9606], Mus musculus (house mouse, species) [taxon 10090], Rattus norvegicus (brown rat, species) [taxon 10116]

## Full text

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Source: https://tomesphere.com/paper/PMC12327283