# The dilemma of food genetics and improvement

**Authors:** Mohamed Zarid

PMC · DOI: 10.1515/biol-2025-1150 · Open Life Sciences · 2025-08-02

## TL;DR

This paper discusses the benefits and challenges of using genetic techniques in food production, emphasizing the need for sustainable and health-focused practices.

## Contribution

The paper introduces a comprehensive analysis of the trade-offs between sensory food qualities and nutritional health benefits in genetic food improvement.

## Key findings

- Genetic methods like CRISPR-Cas9 and marker-assisted selection have limitations and trade-offs in food improvement.
- Prioritizing sensory attributes over nutritional value is a growing concern in food genetics.
- Genetic manipulation may have health implications, including allergenicity and autoimmune risks.

## Abstract

The advancement of genetic techniques in food production offers significant potential for improving crop quality, yield, and sustainability. However, these innovations present a complex set of dilemmas concerning nutritional quality, food authenticity, socioeconomic implications, regulatory challenges, and human health. This article explores contemporary genetic methods such as marker-assisted selection, genome editing (CRISPR-Cas9), and tissue culture, highlighting their applications and limitations. Additionally, transgenic approaches and biofortification strategies are examined for their role in enhancing nutritional value. It examines the trade-offs between organoleptic properties and nutritional integrity, revealing a concerning trend toward prioritizing sensory attributes over health benefits. Furthermore, the potential health implications of genetic manipulation, including links to autoimmune and hormonal disorders, are critically analyzed with a focus on allergenicity concerns and long-term safety assessments. The discussion underscores the urgent need for sustainable practices in food genetics that align with environmental goals and public health priorities. Finally, a call to action is made for collaborative dialogue among scientists, policymakers, and consumers to prioritize health, sustainability, and transparency in food production, ensuring that agricultural advancements benefit all stakeholders while preserving the ecological balance for future generations.

## Full-text entities

- **Diseases:** autoimmune and hormonal disorders (MESH:D001327)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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Source: https://tomesphere.com/paper/PMC12326302