# Efficacy of a feed additive consisting of 6‐phytase produced by (Komagataella phaffii CGMCC 7.370) (VTR‐phytase) for all pigs and growing poultry species (Victory Enzymes GmbH)

**Authors:** Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Montserrat Anguita, Matteo L. Innocenti, Marianna Kujawa, Jordi Ortuño

PMC · DOI: 10.2903/j.efsa.2025.9556 · EFSA Journal · 2025-08-06

## TL;DR

This paper evaluates the effectiveness of a feed additive containing 6-phytase for pigs and poultry, concluding it is potentially effective at specific dosages.

## Contribution

The study provides new evidence supporting the efficacy of VTR-phytase in previously unconfirmed animal species and formulations.

## Key findings

- VTR-phytase is potentially efficacious for poultry for fattening and reared for laying/breeding at 500 U phytase/kg feed.
- The additive is potentially efficacious for reproductive and fattening pigs at 750 U phytase/kg feed.
- Earlier data supported efficacy in laying hens at 1000 U phytase/kg feed.

## Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the efficacy of 6‐phytase produced by Komagataella phaffii CGMCC 7.370 (VTR‐phytase) as a zootechnical feed additive for all pigs and growing poultry species. The additive is intended to be commercialised in two formulations: liquid and powder. In a previous opinion the FEEDAP Panel concluded that the additive is safe for target species, consumers and environment. The FEEDAP Panel deemed that both formulations of the additive are not skin and eyes irritant but should be considered skin and respiratory sensitisers. The FEEDAP Panel concluded that VTR‐phytase has potential to be efficacious in laying hens at 1000 U phytase/kg complete feed, and this conclusion was extended to all laying and reproductive poultry. However, due to the lack of sufficient data, the Panel was not in a position to conclude on the efficacy for poultry for fattening or reared for laying/breeding, and in any porcine species. The applicant provided new trials to support the efficacy of the additive on those target species. Based on the data provided in the previous and current application, the Panel concluded that the additive has a potential to be efficacious as a zootechnical additive for all poultry for fattening and reared for laying/breeding and reproductive porcine species at 500 U phytase/kg complete feed and all porcine species for fattening and reared for reproduction at 750 U phytase/kg complete feed.

## Full-text entities

- **Species:** Gallus gallus (bantam, species) [taxon 9031], Sus scrofa (pig, species) [taxon 9823]

## Full text

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## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC12326181/full.md

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Source: https://tomesphere.com/paper/PMC12326181