# From Pulmonary Hyperlucency to Pulmonary Hypertension: A Case Report of Swyer-James-MacLeod Syndrome

**Authors:** Juan Pablo Montoya L, Juan Vasquez, Ricardo Uribe González, Manuela Guzman-Medina, Valentina Palacio-Arango

PMC · DOI: 10.7759/cureus.87392 · Cureus · 2025-07-06

## TL;DR

This case report describes a rare lung condition called Swyer-James-MacLeod syndrome in an adult who developed pulmonary hypertension.

## Contribution

The novelty lies in presenting a rare case of SJMS with pulmonary hypertension as a complication in an adult patient.

## Key findings

- The patient had a history of childhood respiratory infections leading to SJMS.
- Pulmonary hypertension was identified as a complication of SJMS in this case.
- The case highlights the importance of imaging for diagnosing SJMS due to nonspecific symptoms.

## Abstract

Swyer-James-MacLeod syndrome (SJMS) is a rare condition characterized by unilateral pulmonary hyperlucency and vascular alterations secondary to post-infectious bronchiolitis obliterans. It is also an underdiagnosed disease due to the nonspecificity of its symptoms, which highlights the importance of complementary imaging studies for its identification. Although treatment is mostly conservative, in selected cases, surgical management can improve the prognosis and quality of life of patients. We present the case of an adult female with recurrent respiratory infections in childhood who had an incidental diagnosis of SJMS with pulmonary hypertension as a complication.

## Linked entities

- **Diseases:** Swyer-James-MacLeod syndrome (MONDO:0800120), pulmonary hypertension (MONDO:0005149), bronchiolitis obliterans (MONDO:0015265)

## Full-text entities

- **Diseases:** post-infectious bronchiolitis obliterans (MESH:D001989), Pulmonary Hypertension (MESH:D006976), respiratory infections (MESH:D012141), Pulmonary Hyperlucency (MESH:D019568)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12325120/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12325120/full.md

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Source: https://tomesphere.com/paper/PMC12325120