# Small-world challenges and solutions identified by mid-level managers within a decentralised healthcare system during a qualitative sub-study of a tuberculosis-prevention therapy rollout intervention in Uganda: “When a big drum like the District Health Officer talks”

**Authors:** Jason Johnson-Peretz, Canice Christian, Cecilia Akatukwasa, Fred Atwine, Moses R Kamya, Diane V Havlir, Gabriel Chamie, Carol S Camlin, Elijah Kakande

PMC · DOI: 10.21203/rs.3.rs-5046392/v1 · 2025-07-31

## TL;DR

This study explores how mid-level managers in Uganda's decentralized healthcare system created small-world networks to improve tuberculosis prevention efforts.

## Contribution

It identifies how leadership training fosters small-world networks in decentralized systems to sustain public health campaigns.

## Key findings

- Training mid-level managers improved communication and teamwork, creating denser small-world networks.
- These networks enhanced transparency and accountability across multiple levels of the healthcare system.
- Increased collaboration led to faster dissemination of best practices for tuberculosis prevention.

## Abstract

Decentralisation policies that devolve certain administrative and decision-making powers to local levels can pose challenges for public health and healthcare systems. For a decentralised health system to function optimally, mid-level systems must rely on tightly clustered, so-called “small-world” networks to efficiently scale-up national health campaigns and share best practices. Few studies have qualitatively tackled the mechanisms of small-world creation and their potential effects on public health promotion during centralized national campaigns in a decentralised, mid-level healthcare system tier.

We performed a thematic analysis using a rigorous and accelerated data reduction (RADaR) technique on 23 in-depth interviews and six focus group discussions with mid-level healthcare managers in a cluster-randomised trial from 2019 to 2021, whose intervention component aimed to increase isoniazid preventive therapy (IPT) uptake to prevent tuberculosis among people living with HIV in Uganda.

Training mid-level managers on management and leadership skills fostered the creation of small-world networks within a decentralised healthcare context and promoted mid-level manager agency to address several drawbacks associated with the decentralisation of healthcare systems. Through improved communication, intervention groups encouraged teamwork within their districts, building a denser cluster of networks. This in turn fostered small world ties that paired transparency with a sense of reciprocal accountability moving in multiple directions, upwards to the Ministry of Health (MoH), downwards towards local communities, and horizontally towards peers.

Increased collaboration demonstrably strengthened the clustering of small-world network ties at a horizontal level to disseminate knowledge of best practices more quickly and efficiently in promoting the uptake of IPT while ensuring accountability to peers, the MoH, and local communities, sustaining these levels after a centralized national campaign ended.

NCT03315962. Registered 20 October, 2017

## Linked entities

- **Chemicals:** isoniazid (PubChem CID 3767)
- **Diseases:** tuberculosis (MONDO:0018076)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** tuberculosis (MESH:D014376), HIV (MESH:D015658)
- **Chemicals:** isoniazid (MESH:D007538)

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Source: https://tomesphere.com/paper/PMC12324578